Shido Tatsuhiko

The main character, Shido is a private detective and vampire who has the ability to form weapons out of his own blood. Shido has an outwardly mercurial personality, but beneath that, he is very serious and dedicated so much so that he is likely to blame himself when something goes wrong. He protects the humans from the nightbreeds in order to atone for his past crimes early in his vampiric life. He is often employed by Yayoi Matsunaga, an agent of the NOS, to solve Nightbreed related crimes.

He was turned into a vampire by Cain, an ancient vampire; however, Cain's arrogance and cruelty made him leave his sire. Cain refuses to let go of Shido and continues to follow him. Cain was responsible for, among other things, fatally wounding Riho Yamazaki and forcing Shido to turn her into a vampire to save her.

Voiced By: Takumi Yamazaki (Japanese); Richard Cansino (English)